How can I call client side C# program function via JavaScript from web page on server side?

I am trying to create a webapp which is capable of reaching client side local resources.

I.e. I am going to install exe to client's computer. I want to fire this exe's function via JavaScript code (which is on the remote server) and fire a function that connects to a serial port, reads data and returns that data to a web page.

I can write C# or Visual Basic for client side app.

I was able to get some result via XMLHttpRequest so far. I opened port 9091 with C# and able to connect that port via writing localhost:9091 to browser's address bar and get data but I wasn't able to do it with JavaScript. (Getting CORS error)

Is it possible to accomplish this task with my skill set?

Example for client side app

Imports System.Net
Imports System.Globalization
Imports System.Collections.Specialized

Module HttpListener

    Sub Main()
        Dim prefixes(0) As String
        prefixes(0) = "http://*:9091/"
        ProcessRequests(prefixes)
    End Sub

    Private Sub ProcessRequests(ByVal prefixes() As String)
        If Not System.Net.HttpListener.IsSupported Then
            Console.WriteLine( _
                "Windows XP SP2, Server 2003, or higher is required to " & _
                "use the HttpListener class.")
            Exit Sub
        End If

        ' URI prefixes are required,
        If prefixes Is Nothing OrElse prefixes.Length = 0 Then
            Throw New ArgumentException("prefixes")
        End If

        ' Create a listener and add the prefixes.
        Dim listener As System.Net.HttpListener = _
            New System.Net.HttpListener()
        For Each s As String In prefixes
            listener.Prefixes.Add(s)
        Next

        Try
            ' Start the listener to begin listening for requests.
            listener.Start()
            Console.WriteLine("Listening...")

            ' Set the number of requests this application will handle.
            Dim numRequestsToBeHandled As Integer = 10

            For i As Integer = 0 To numRequestsToBeHandled
                Dim response As HttpListenerResponse = Nothing
                Try
                    ' Note: GetContext blocks while waiting for a request.

                    Dim context As HttpListenerContext = listener.GetContext()

                    ' Create the response.
                    response = context.Response

                    Dim IncMessage As New NameValueCollection
                    IncMessage = context.Request.QueryString

                    Dim Field As String
                    Dim FValue As String
                    Dim Values() As String

                    For Each key As String In IncMessage.Keys
                        Values = IncMessage.GetValues(key)
                        Field = key
                        For Each value In Values
                            FValue = value

                            MsgBox(Field & " equals " & FValue)
                        Next value
                    Next key


                Catch ex As HttpListenerException
                    Console.WriteLine(ex.Message)
                Finally
                    If response IsNot Nothing Then
                        response.Close()
                    End If
                End Try
            Next
        Catch ex As HttpListenerException
            Console.WriteLine(ex.Message)
        Finally
            ' Stop listening for requests.
            listener.Close()
            Console.WriteLine("Done Listening...")
        End Try
    End Sub

End Module