you can use Alamofire 3.0+ below code

func uploadImageAndData(){
    //parameters
    let gender    = "M"
    let firstName = "firstName"
    let lastName  = "lastName"
    let dob       = "11-Jan-2000"
    let aboutme   = "aboutme"
    let token     = "token"

    var parameters = [String:AnyObject]()
    parameters = ["gender":gender,
                  "firstName":firstName,
                  "dob":dob,
                  "aboutme":about,
                  "token":token,
                  "lastName":lastName]

    let URL = "http://yourserviceurl/"
    let image = UIImage(named: "image.png")

    Alamofire.upload(.POST, URL, multipartFormData: {
        multipartFormData in

        if let imageData = UIImageJPEGRepresentation(image, 0.6) {
            multipartFormData.appendBodyPart(data: imageData, name: "image", fileName: "file.png", mimeType: "image/png")
        }

        for (key, value) in parameters {
            multipartFormData.appendBodyPart(data: value.dataUsingEncoding(NSUTF8StringEncoding)!, name: key)
        }
    }, encodingCompletion: {
        encodingResult in

        switch encodingResult {
        case .Success(let upload, _, _):
            print("s")
            upload.responseJSON { 
                response in
                print(response.request)  // original URL request
                print(response.response) // URL response
                print(response.data)     // server data
                print(response.result)   // result of response serialization

                if let JSON = response.result.value {
                    print("JSON: \(JSON)")
                }
            }
        case .Failure(let encodingError):
            print(encodingError)
        }
    })
}

SWIFT 2 AlamoFire Simple Image Upload (REST API)

@amit gupta It seems answer contains big overhead. AlamoFire contain load of simplified solution. Alamofire.request method contains several simplified overload which can use to upload in simple manner. By using Alamofire.request( method developer can get rid of encoding overhead.

HTTP Status 415 gives because of not specifying the correct media type.

Please check my solution below.

import UIKit
import Alamofire

class ViewController: UIViewController {

    @IBOutlet var imageView: UIImageView!
    @IBOutlet var btnUpload: UIButton!
    override func viewDidLoad() {
        super.viewDidLoad()
    }

    func successDataHandler(responseData:String){

        print ("IMAGE UPLOAD SUCCESSFUL    !!!")

    }

    func failureDataHandler(errorData:String){

        print ("  !!!   IMAGE UPLOAD FAILURE   !!! ")

    }

    @IBAction func actionUpload(sender: AnyObject) {

        let URL = "http://m8coreapibeta.azurewebsites.net/api/cards/SaveImages"

        let postDataProlife:[String:AnyObject] = ["CardId":(dataCardDetail?.userId)!,"ImageType":1,"ImageData":imageView.image!]

        uplaodImageData(URL, postData: postDataProlife, successHandler: successDataHandler, failureHandler: failureDataHandler)
    }

    func uplaodImageData(RequestURL: String,postData:[String:AnyObject]?,successHandler: (String) -> (),failureHandler: (String) -> ()) -> () {

        let headerData:[String : String] = ["Content-Type":"application/json"]

        Alamofire.request(.POST,RequestURL, parameters: postData, encoding: .URLEncodedInURL, headers: headerData).responseString{ response in
            switch response.result {
            case .Success:
                print(response.response?.statusCode)
                successHandler(response.result.value!)
            case .Failure(let error):
                failureHandler("\(error)")
            }
        }
    }

    override func didReceiveMemoryWarning() {
        super.didReceiveMemoryWarning()
        // Dispose of any resources that can be recreated.
    }


}

Almaofire with swift 3.0

Alamofire.upload(multipartFormData: { multipartFormData in
    var index = 1
    for image in imageArray {
        let imageData: Data = (UIImageJPEGRepresentation(image, 1.0) as Data?)!

        multipartFormData.append(imageData, withName: "home-\(index)", fileName: "home-\(index)", mimeType: "image/jpeg")

        index += 1
    }
    }, with: requestName, encodingCompletion: { result in
        switch result {
        case .success(let upload, _, _):

            upload.responseJSON { response in
                print("Image(s) Uploaded successfully:\(response)")
            }
        case .failure(let encodingError):
            print("encodingError:\(encodingError)")
        }
})

Swift 4 with Alamofire 4

let isConnected = connectivity.isConnectedToInternet()

  func updateProfile(firstName:String,lastName:String ,imageData:Data?,completion: @escaping (isValidUser)->()) {


    if self.isConnected {

        var parameters : [String:String] = [:]
        parameters["auth_key"] = loginUser?.authKey!
        parameters["first_name"] = firstName
        parameters["last_name"] = lastName

        let url = "\(baseUrl)\(basicAuthenticationUrl.updateProfile)"
        print(url)


        Alamofire.upload(multipartFormData: { (multipartFormData) in
            for (key, value) in parameters {
                multipartFormData.append("\(value)".data(using: String.Encoding.utf8)!, withName: key as String)
            }

            if let data = imageData {
                multipartFormData.append(data, withName: "image_url", fileName: "image.png", mimeType: "image/png")
            }

        }, usingThreshold: UInt64.init(), to: url, method: .post) { (result) in
            switch result{
            case .success(let upload, _, _):
                upload.responseJSON { response in
                    print("Succesfully uploaded  = \(response)")
                    if let err = response.error{

                        print(err)
                        return
                    }

                }
            case .failure(let error):
                print("Error in upload: \(error.localizedDescription)")

            }
        }
    }

}

Almaofire with swift 2.0 just copy and paste below code.here m asumming JSON response from server

 func uploadImageRemote (imageData : NSData?) -> Dictionary <String,AnyObject>{
    var imageDictionary = Dictionary<String,AnyObject>()

      var tokenHeaders:[String:String]! = ["x-access-token":Constants.kUserDefaults.stringForKey("userToken")!]
    Alamofire.upload(
        .POST,
        "http://52.26.230.146:3300/api/profiles/imageUpload",headers:tokenHeaders,
        multipartFormData: { multipartFormData in
            multipartFormData.appendBodyPart(data: imageData!, name: "upload", fileName: "imageFileName.jpg", mimeType: "image/jpeg")
        },
        encodingCompletion: { encodingResult in
            switch encodingResult {
            case .Success(let upload, _, _):
                upload.progress { (bytesWritten, totalBytesWritten, totalBytesExpectedToWrite) in
                    print("Uploading Avatar \(totalBytesWritten) / \(totalBytesExpectedToWrite)")
                    dispatch_async(dispatch_get_main_queue(),{

                    })
                }
                upload.responseJSON { response in
                    guard response.result.error == nil else {
                        print("error calling GET \(response.result.error!)")
                        return
                    }

                    if let value = response.result.value {
                       print("Success JSON is:\(value)")
                        if let result = value as? Dictionary<String, AnyObject> {
                            imageDictionary["imageUrl"] = result["url"]
                        }
                    }

                    dispatch_async(dispatch_get_main_queue(),{
                        //Show Alert in UI
                        print("Avatar uploaded");
                    })
                }

            case .Failure(let encodingError):
                //Show Alert in UI
                print("Avatar not uploaded \(encodingError)");
            }
        }
    );



return imageDictionary
}

To use encoding Parameters, make a ParameterEncoding variable, assign it a encoding type (case of the enum which include .JSON, .URL) and then use the encode function with your NSURLRequest and the parameters. This function returns a tuple of two element, the first being the resulting NSURLRequest and the second being the resulting possible NSError.

Here's how I used it for a custom header I needed in a project

 var parameterEncoding:ParameterEncoding!
    switch method {
        case .POST, .PUT :
            parameterEncoding = ParameterEncoding.JSON
        default :
            parameterEncoding = ParameterEncoding.URL
    }
    var alamoRequest = Alamofire.Manager.sharedInstance.request(parameterEncoding.encode(mutableURLRequest, parameters: parameters).0)