I'm going to assume you're talking about in a web browser.
JavaScript in web browsers has a single main UI thread, and then zero or more web worker threads. Web workers are indeed isolated from the main UI thread (and each other) and so don't have access to globals (other than their own). This is intentional, it makes both implementing the environment and using it dramatically simpler and less error-prone. (Even if that isolation weren't enforced, it's good practice for multi-threaded programming anyway.) You send messages to, and receive messages from, web workers via postMessage and the message event.
JavaScript threads (the main UI thread and any web workers) work via a thread-specific task queue (aka "job queue"): Anything that needs to happen on a JavaScript thread (the initial run of the code when a page loads, handling of an event, timer callbacks [more below]) adds a task to the queue. The JavaScript engine runs a loop: Pick up the next task, run it, pick up the next, run it, etc. When there are no tasks, the thread goes quiet waiting for a task to arrive.
setTimeout doesn't create a separate thread, it just schedules a task (a call to a callback) to be added to the task queue for that same thread after a delay (the timeout). Once the timeout occurs, the task is queued, and when the task reaches the front of the queue the thread will handle it.
setInterval does exactly what setTimeout does, but schedules a recurring callback: Once the timeout occurs, it queues the task, then sets up another timeout to queue the task again later. (The rules around the timing are a bit complex.)
If you just want something to recur, forever, at intervals, and you want that thing to have access to global variables in the main UI thread, then you either:
Use setInterval once, which will set up recurring calls back to your code, or
Use setTimeout, and every time you get your callback, use setTimeout again to schedule the next one.
From your description, it sounds as though you may be calling setInterval more than once (for instance, on each callback), which quickly bogs down the thread as you're constantly telling it to do more and more work.
setIntervalis internally the same assetTimeoutexcept thatsetTimeoutonly runs once, butsetIntervalwill restart the time after the end of each execution.