In rails 4:
@followed = current_user.followed_user_ids # @followed = [11,3,24,42]
@not_followed = User.where.not(id: @followed)
This should generate something like select * from users where id not in (11,3,24,42)
As you comment, you are using find_by_slq (and that is available in all rails versions). Then you could use the join method:
query = "select * from users where id not in (#{@followed.join(',')})"
This would raise mysql errors if @followed is blank, the resulting query would be
select * from users where id not in ()
To solve this whiout specifiying aditional if statements to your code, you can use:
query = "select * from users where id not in (0#{@followed.join(',')})"
Your normal queries would be like:
select * from users where id not in (01,2,3,4)
but if the array is blank then would result in
select * from users where id not in (0)
which is a still valid sql statement and is delivering no results (which might be the expected situation in your scenario).