If you need multiple conditions, just separate them with AND:
... WHERE table1.age <= ? AND table1.region = ?
No need to use WHERE again. Just like you wouldn't need to use if() more than once if you were writing a complex condition in PHP.
PS: This isn't directly related to your question, but you should get into the habit of not putting $_POST or $_GET variables directly into your SQL queries. It's a good way to get hacked! Ask your tutor about "SQL injection," or read my presentation SQL Injection Myths and Fallacies.
I know you're just starting out, but if you were training to be an electrician, you would place a high priority on learning how to avoid being electrocuted or how to avoid causing a fire.
Here's how I would write your query using mysqli. One advantage of using query parameters is you never need to worry about where you start and end your quotes.
$query = "SELECT * from table1 where table1.age <= ? AND table1.region = ?";
$stmt = $mysqli->prepare($query) or trigger_error($mysqli->error, E_USER_ERROR);
$stmt->bind_param("is", $_POST["min_age"], $_POST["region"]);
$stmt->execute() or trigger_error($stmt->error, E_USER_ERROR);
The other good habit I'm showing here is to always report if prepare() or execute() return an error.
If you must interpolate variables into your SQL, first make sure you protect the variables either by coercing the value to an integer, or else by using a proper escaping function like mysqli_real_escape_string(). Don't put $_POST variables directly into the string. Also you don't have to stop and restart the quotes if you use PHP's syntax for embedding variables directly in double-quoted strings:
$age = (int) $_POST["min_age"];
$region = $mysqli->real_escape_string($_POST["region"]);
$query = "SELECT * from table1 where table1.age <= {$age}
AND table1.region = '{$region}'";
