I assume this code is supposed to extract the red value from a RGB color value stored as a 24 bit unsigned integer, with red in te high bits and blue in the low bits. So mask needs to be 255 (0xff in hexadecimal) to capture the 8 bits of data from the red channel after we shift them into place.
Here's a small Numpy demo.
import numpy as np
np.set_printoptions(formatter={'int': hex})
colors = np.array([0x123456, 0x789abc, 0xdef012, 1884829820], dtype=np.uint32)
print(colors, colors.dtype)
mask = 255
reds = ((colors >>16) & mask).astype(np.uint8)
print(reds, reds.dtype)
output
[0x123456 0x789abc 0xdef012 0x7058387c] uint32
[0x12 0x78 0xde 0x58] uint8
I've used hex output to make it clear that we're actually getting the red channel bits. Note that 0x58 == 88 in decimal.
maskis 256? A mask of 255 (0xff) would make more sense.